Table 2. All traits tested in NIL and CSS assays.
| PC | Hotspot | Correlated traits | Correlation range |
|---|---|---|---|
| Carmustine.PC1 | V | mean.EXT, mean.TOF, q75.EXT, median.EXT, median.TOF, q75.TOF, median.norm.EXT, q90.TOF, q90.EXT | 0.72–0.95 |
| Carmustine.PC6 | IVL | q25.norm.EXT, q10.norm.EXT | 0.33–0.39 |
| Chlorothalonil.PC1 | V | mean.EXT, q75.EXT, mean.TOF, median.EXT, median.TOF, q75.TOF | 0.73–0.95 |
| Chlorothalonil.PC2 | IVL | cv.TOF, cv.EXT | 0.72–0.90 |
| Chlorothalonil.PC3 | IVL, IVR | mean.norm.EXT, q75.norm.EXT, q90.norm.EXT, median.norm.EXT | 0.50–0.65 |
| Cisplatin.PC1 | IVL, V | mean.EXT, mean.TOF, median.EXT, median.TOF, q75.TOF, q75.EXT, q90.EXT, q90.TOF | 0.78–0.97 |
| Cisplatin.PC3 | IVL | var.TOF, var.EXT | 0.38–0.54 |
| Cisplatin.PC4 | V | norm.n, n | 0.76–0.80 |
| Fluoxetine.PC1 | IVR | mean.norm.EXT, q75.norm.EXT, mean.EXT, q75.EXT, q90.norm.EXT, q90.EXT | 0.79–0.96 |
| Fluoxetine.PC5 | IVR | q90.norm.EXT, q75.norm.EXT, mean.norm.EXT, q75.EXT, mean.EXT, q90.EXT | 0.07–0.40 |
| Irinotecan.PC2 | IVR | cv.TOF, cv.EXT | 0.57–0.84 |
| Paraquat.PC1 | V | median.EXT, mean.EXT, q25.EXT, q75.EXT, mean.TOF, q75.TOF, q10.EXT, q90.EXT, q90.TOF, median.TOF, q25.TOF, q10.TOF | 0.75–0.95 |
| Silver.PC1 | V | mean.EXT, median.EXT, q75.EXT, mean.TOF, q90.EXT, q90.TOF, median.TOF, q75.TOF | 0.77–0.96 |
| Silver.PC3 | IVL | q10.norm.EXT, q25.norm.EXT, mean.norm.EXT, median.norm.EXT, q75.norm.EXT, q90.norm.EXT | 0.32–0.64 |
| Silver.PC4 | IVL | n, norm.n | 0.84–0.84 |
| Silver.PC5 | IVL | n, norm.n | 0.41–0.41 |
| Tunicamycin.PC1 | IVL | median.EXT, q75.EXT, mean.TOF, q75.TOF, median.TOF, median.norm.EXT, q90.EXT, q90.TOF, mean.EXT, q75.norm.EXT, mean.norm.EXT, q25.norm.EXT, q90.norm.EXT, q10.norm.EXT | 0.69–0.96 |
| Tunicamycin.PC3 | IVL | norm.n, n | 0.47–0.50 |
PC, principal component; V, hotspot on the center of chromosome V; EXT, extinction; TOF, time of flight; IVL, hotspot on the center of chromosome IV; IVR, hotspot on the right of chromosome IV.