Table 3. Results of isoprenylation prediction algorithms.
| Isoprenylation prediction (%) | ||||
|---|---|---|---|---|
| Test set | Method | High | Ambiguous | Low |
| Ydj1-based (n = 153) | FlexPepBind | 27a | 20 | 54 |
| PrePS | 7 | 25 | 68 | |
| in-house | 86 | 14 | 0 | |
| Ras-based (n = 369) | FlexPepBind | 60 | 15 | 25 |
| PrePS | 56 | 32 | 12 | |
| in-house | 86 | 14 | 0 | |
| Cxxx (n = 8000) | FlexPepBind | 17 | 12 | 71 |
| PrePS | 5 | 14 | 80 | |
| in-house | 42 | 28 | 30 | |
| SGD (n = 89)b | FlexPepBind | 28 | 27 | 46 |
| PrePS | 26 | 8 | 66 | |
| in-house | 61 | 16 | 24 | |
a
The summed value of the three categories for some sets exceeds 100% due to rounding errors.
b
This test set was identified using appropriate sequence patterns and the Pattern Match search function associated with the Saccharomyces Genome Database (SGD). The set was culled of sequences annotated as dubious open reading frames.