Table 6.

Subgroup analyses of primary outcome (major bleeding after day 30) in the 4457 Patients available for primary analysis

	Patients available for primary analysis
	Male patients	Female patients	Cancer	No cancer	Age <60 years	Age ≥60 years
Crude OR for 1‐point score increase (95% CI)	1·4 (1·1–1·7)	1·6 (1·2–2·1)	1·0 (0·61–1·7)	1·5 (1·2–2·0)	1·5 (0·85–2·7)	1·4 (1·1–1·9)
Adjusted OR for 1‐point score increase (95% CI)	1·3 (1·0–1·6)	1·5 (1·1–2·0)	1·0 (0·60–1·7)	1·5 (1·1–1·9)	1·3 (0·75–2·4)	1·4 (1·0–1·8)
Crude HR ≥2 points (95% CI)	2·2 (0·89–5·2)	3·6 (1·2–10)	n.a.	2·0 (0·91–4·5)	4·2 (0·89–20)	2·5 (1·0–6·0)
Adjusted HR ≥2 points (95% CI)	1·8 (0·72–4·4)	3·3 (1·1–9·8)	n.a.	1·8 (0·82–4·1)	3·3 (0·68–15·9)	1·7 (0·7–4·4)
C‐statistic (95% CI)	0·66 (0·55–0·77)	0·71 (0·56–0·86)	0·53 (0·33–0·73)	0·65 (0·54–0·76)	0·61 (0·42–0·80)	0·64 (0·53–0·76)

95% CI, 95% confidence interval; HR, hazard ratio; n.a., not applicable; OR, odds ratio.