Table 2.
Agreement between MoBa and NorPD by trimester, pregestational period, and gestational period
| THRT | MoBa totala | NorPD totala | MoBa only | NorPD only | Both | Neither | Agreement | |||
|---|---|---|---|---|---|---|---|---|---|---|
| n | % | N | % | n | n | n | n | κb (95% CI) | Rangec | |
| 6 months prior to LMP | 1,001 | 1.8 | 1,198 | 2.1 | 48 | 245 | 953 | 54,902 | 0.86 (0.85–0.88) | P |
| First trimester | 1,004 | 1.8 | 1,129 | 2.0 | 111 | 236 | 893 | 54,908 | 0.83 (0.82–0.85) | P |
| Second trimesterd | 1,077 | 1.9 | 1,224 | 2.2 | 56 | 203 | 1,021 | 54,868 | 0.89 (0.87–0.90) | P |
| Third trimester | 557 | 1.0 | 1,165 | 2.1 | 64 | 672 | 493 | 54,919 | 0.57 (0.54–0.59) | m |
| Gestational periode | 1,141 | 2.0 | 1,325 | 2.3 | 21 | 205 | 1,120 | 54,802 | 0.91 (0.89–0.92) | P |
Notes:
a
Total study population, n=56,148.
b
Cohen’s kappa coefficient (k).
c
Subdivision of agreement by Landis and Koch: <0, no (no); 0–0.20, slight (s); 0.21–0.40, fair (f); 0.41–0.60, moderate (m); 0.61–0.80, substantial (S); and 0.81–1.00, perfect (P).
d
Weeks 13–16 aggregate the text box “week 13+” from MoBa Q1 and “weeks 13–16” from MoBa Q3.
e
LMP to delivery.
Abbreviations: LMP, last menstrual period; MoBa, Norwegian Mother and Child Cohort Study; MoBa Q1, MoBa questionnaire 1; MoBa Q3, MoBa questionnaire 3; NorPD, Norwegian Prescription Database; THRT, thyroid hormone replacement therapy.