Table 4.
Drug utilization in the adherence groups
| Adherence groups | ||||
|---|---|---|---|---|
| Drug utilization (mean ± SE) | Decreasing- Low, n=70 (5.8%) | Increasing- Medium, n=128 (11.0%) | Constant- Medium, n=381 (32.9%) | Constant- High, n=592 (50.2%) |
| DDD during gestation | 55±5.62 | 112±6.09 | 129±3.64 | 251±3.66 |
| PDCa during gestation | 0.20±0.02 | 0.40±0.02 | 0.45±0.01 | 0.82±0.01 |
| Medication gapsb during gestation | 0.71±0.10 | 0.88±0.09 | 1.28±0.06 | 1.01±0.04 |
| Prescriptions during gestation | 1.60±0.13 | 2.64±0.09 | 2.55±0.05 | 3.13±0.04 |
| Prescriptions 6 months prior to LMP | 3.44±0.50 | 1.18±0.21 | 5.95±0.19 | 7.80±0.18 |
| DDD 6 months prior to LMP | 34±5.49 | 4±0.88 | 78±2.41 | 139±2.55 |
Notes:
a
PDC, total sum of DDDs during gestation/length of gestation in days.
b
Medication gap is break of 14 days between the previous and next dispensed prescription.
Abbreviations: DDD, defined daily dose; LMP, last menstrual period; PDC, proportion of days covered; SE, standard error.