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. Author manuscript; available in PMC: 2018 Dec 6.
Published in final edited form as: Nature. 2017 Nov 8;551(7680):327–332. doi: 10.1038/nature24487

Figure 1. Regeneration of the transgenic epidermis.

Figure 1

a, Clinical picture of the patient showing massive epidermal loss. b, Schematic representation of the clinical picture. The denuded skin is indicated in red, while blistering areas are indicated in green. Flesh-colored areas indicate currently non-blistering skin. Transgenic grafts were applied on both red and green areas. c, Restoration of patient’s entire epidermis, with the exception of very few areas on the right thigh, buttocks, upper shoulders/neck and left axilla (asterisks, altogether ≤2% of TBSA). d, Normal skin functionality and elasticity. e, Absence of blister formation at sites where some of post-graft biopsies were taken (arrow).