Extended Data Table 2.
Clonal analysis was performed on pre-graft cultures (PGc), a graft ready for transplantation (Graft) and on primary cultures established at 4 (4Mc) and 8 (8Mc1) months after grafting. H, M and P indicate holoclones, meroclones and paraclones, respectively. Frequency indicates the percentage of holoclones detected in the population of clonogenic keratinocytes. Graft was not used for LAM-PCR or NGS analyses but for holoclone quantification as part of quality control.
| ID sample | ID replicate | Total number of clones | H | M/P | H Frequency (%) |
|---|---|---|---|---|---|
| PGc | PG-1 | 88 | 10 | 78 | 11.36 |
| PG-2 | 63 | 4 | 59 | 6.35 | |
| PG-3 | 62 | 3 | 59 | 4.84 | |
| PG-4 | 66 | 3 | 63 | 4.55 | |
| Total | 279 | 20 | 259 | 7.17 | |
| Graft | Graft | 95 | 4 | 91 | 4.21 |
| 4Mc | 4Mc-1 | 121 | 8 | 113 | 6.61 |
| 4Mc-2 | 105 | 5 | 100 | 4.76 | |
| 4Mc-3 | 52 | 1 | 51 | 1.92 | |
| Total | 278 | 14 | 264 | 5.04 | |
| 8Mc1 | 8Mc1-1 | 56 | 4 | 52 | 7.14 |
| 8Mc1-2 | 74 | 3 | 71 | 4.05 | |
| Total | 130 | 7 | 123 | 5.38 | |