Fig. 1.

(A) Motif deconvolution analysis with MixMHCp and GibbsCluster of the 9-mer LM_UniProt and LM_spliced peptides, and comparison to known logos from Immune Epitope Database and Analysis resource (IEDB) for HLA-A03:01, HLA-A23:01, and HLA-B08:01 (HLA-B15:18 has no experimental ligands in IEDB). Motifs found in LM_UniProt peptides are highly reproducible and comparable to the known motifs from IEDB, while this is not the case for motifs found in LM_spliced peptides. (B) Length distribution of the LM_UniProt and LM_spliced peptide. (C) Rate of differing PSMs for the peptides in LM_UniProt and LM_spliced. Only MS/MS scans where both search strategies reported a match at FDR of 1% were considered.