Table 1.
Characteristics (Lagged One Wave) of the Study Sample Aged 65–88 at T1–T6 and With Data on PCD and MMSE ≤22 at Study entry
| Characteristics (pooled) | T1 (1992/1993), n = 1,800 | T2 (1995/1996), n = 1,565 | T3 (1998/1999), n = 1,420 | T4 (2001/2002), n = 1,085 | T5 (2005/2006), n = 1,150 | T6 (2008/2009), n = 1,120 |
|---|---|---|---|---|---|---|
| Education, in years, mean (SD) | 8.81 (3.30) | 8.98 (3.24) | 9.15 (3.26) | 9.33 (3.26) | 9.96 (3.40) | 10.27 (3.41) |
| Cardiovascular disease, yes, % (n) | 26.33 (474) | 25.07 (392.4) | 25.56 (363.0) | 28.40 (308.1) | 28.83 (331.5) | 32.23 (361) |
| Diabetes mellitus, yes, % (n) | 5.93 (106.8) | 6.28 (98.3) | 7.60 (107.9) | 9.58 (103.9) | 11.77 (135.3) | 12.41 (139) |
| High blood pressure, yes, % (n) | 27.69 (498.5) | 68.33 (1069.4) | 68.68 (975.3) | 59.14 (641.7) | 61.86 (711.4) | 50.58 (566.5) |
| Use of anti-hypertensive, yes, % (n) | 26.64 (479.5) | 30.23 (473.1) | 34.89 (495.4) | 39.76 (431.4) | 47.14 (542.1) | 48.25 (540.4) |
| Alcohol use | ||||||
| No | 21.59 (388.7) | 23.11 (361.6) | 18.68 (265.2) | 18.06 (196) | 16.33 (187.8) | 16.04 (179.7) |
| Middle | 70.52 (1269.4) | 65.81 (1030) | 70.74 (1004.5) | 71.64 (777.3) | 71.51 (822.4) | 72.07 (807.2) |
| High | 7.88 (141.8) | 11.08 (173.4) | 10.58 (150.3) | 10.29 (111.7) | 12.16 (139.8) | 11.88 (133.1) |
| Smoking status, smoker, % (n) | 38.18 (687.2) | 32.68 (511.5) | 26.52 (376.6) | 28.53 (309.5) | 22.48 (258.5) | 26.48 (296.6) |
| Body mass index mean (SD) | 26.51 (24.17–29.31) | 26.62 (24.17–29.19) | 26.90 (24.45–29.49) | 26.76 (24.56–29.76) | 27.05 (24.78–30.02) | 26.97 (24.66–30.10) |
| Physical activity, min/day, median (interquartile range) | 140.96 (79.87–218.43) | 142.13 (86.97–210.64) | 140.63 (82.60–210.98) | 139.35 (81.91–208.76) | 132.92 (83.70–199.22) | 135.40 (83.59–198.09) |
| Clinically relevant depressive symptoms, yes, % (n) | 13.47 (242.4) | 13.42 (210.0) | 15.10 (214.4) | 13.96 (151.5) | 14.29 (164.3) | 10.47 (117.3) |
Note. PCD = persistent cognitive decline; MMSE = Mini-Mental Status Examination; SD = standard deviation.