Table 4. Comparative IC50 for antimonial against in vivo recovered promastigotes.
WT | R + vehicle | R + 2HF | R + A | |
---|---|---|---|---|
IC50 | 25.33 μM | 157.9 μM | 212 μM | 122 μM |
Resistance fold | - | 6.2 | 8.4 | 5 |
WT: wild-type; R: antimony-resistant; 2HF: 2’-Hydroxyflavanone; A: meglumine antimonial