Figure 2.
In vitro screening in intestinal and filarial nematodes. (A) Compounds screened to identify their pan-phylum potential based on motility inhibition. For complete set of results and details on the molecular weight and tested concentrations see Table S4. Dose response assay data for 6a and its analogs 6c and 6d from in vitro screening of whipworm (B) and filarial nematode (C). This is a subset compiled from the full dataset to illustrate the most striking results.