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. Author manuscript; available in PMC: 2019 Jul 13.
Published in final edited form as: ACS Infect Dis. 2018 May 14;4(7):1130–1145. doi: 10.1021/acsinfecdis.8b00090

Scheme 1.

Scheme 1

Synthesis of known mammalian small molecule CPT inhibitors and analogs. (A) Synthesis of known compound 6a and its newly designed analogs. (B) Synthesis of known compound 10a and its newly designed analogs.