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. 2017 Dec 14;159(2):1159–1171. doi: 10.1210/en.2017-00582

Table 2.

Responsiveness of THAI #4 and 23 Mouse Lines to T3

THAI #4 (T3)
Tissue Eu (RLU/mg Protein) Hyper (RLU/mg Protein) Fold (Means ± SEM) P Value
Liver 0.003 0.017 5.0 ± 0.6 0.009a
Heart 0.006 0.284 45.9 ± 5.65 0.002a
#23 (T3)
Tissue Eu (RLU/mg Protein) Hyper (RLU/mg Protein) Fold (Means ± SEM) P Value
MBH 0.18 2.222 12.31 ± 2.4 0.003a

Euthyroid animals were treated with L-T3 (IP 1 μg/g bw for 1 day). Luciferase activity was assessed in tissue samples with luciferase assay and expressed as RLU per milligram protein. Luciferase activity of corresponding tissues of TH vs vehicle-treated animals was performed by Student t test (n ≥ 4).

Abbreviation: MBH, mediobasal hypothalamus.

a

P < 0.05.