Table 1.

Predictors of Early Nonremission

Variables	OR	95% CI	Standard Error	P Value	Adjusted OR	Adjusted P Value
Demographics
Age	1.0	1.0, 1.0	0.01	0.002	—	—
BMI	1.0	1.0, 1.1	0.02	0.097	—	—
Sex	0.7	0.4, 1.5	0.27	0.403	—	—
Path confirmed	0.5	0.2, 1.1	0.21	0.102	—	—
White	0.8	0.4, 1.7	0.30	0.570	—	—
Black	1.5	0.6, 3.7	0.70	0.364	—	—
Asian	—	—	—	—	—	—
Cortisol
Post-CRH % change	1.0	1.0, 1.0	0.00	0.604	1.0	0.614
Post-CRH avg	1.0	1.0, 1.0	0.02	0.685	1.0	0.721
Post-CRH max	1.0	1.0, 1.0	0.02	0.961	1.0	0.858
POD-0 at noon	1.0	1.0, 1.1	0.02	0.034	1.0	0.165
POD-0 at 6 pm	1.1	1.0, 1.1	0.02	<0.001	1.1	<0.001
POD-0 avg	1.1	1.0, 1.1	0.02	<0.001	1.1	<0.001
POD-1 at midnight	1.1	1.0, 1.1	0.02	<0.001	1.1	<0.001
POD-1 at 6 am	1.2	1.1, 1.2	0.03	<0.001	1.2	<0.001
ACTH
Post-CRH % change	1.0	1.0, 1.0	0.00	0.287	1.0	0.528
Post-CRH avg	1.0	1.0, 1.0	0.00	0.244	1.0	0.333
Post-CRH max	1.0	1.0, 1.0	0.00	0.213	1.0	0.309
POD-0 at noon	1.0	1.0, 1.0	0.00	0.054	1.0	0.082
POD-0 at 6 pm	1.0	1.0, 1.0	0.00	0.021	1.0	0.025
POD-0 avg	1.0	1.0, 1.0	0.00	0.005	1.0	0.007
POD-1 at midnight	1.0	1.0, 1.0	0.01	0.019	1.0	0.035
POD-1 at 6 am	1.0	1.0, 1.1	0.01	<0.001	1.0	0.001

Nonremission was defined as no postoperative cortisol level <5 μg/dL within 10 days of surgery. Results from univariable or multivariable logistic regression adjusting for age, sex, and BMI, with nonremission as the dependent variable.

Abbreviations: avg, average; max, maximum.