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. 2017 Oct 10;159(1):323–340. doi: 10.1210/en.2017-00738

Figure 8.

Figure 8.

DKO mice showed insulin resistance and moderate hyperinsulinemia. (a) Glucose tolerance test (GTT), insulin tolerance test (ITT), and insulin plasma levels from 3-month-old WT (GTT, n = 22; ITT, n = 23; insulin plasma levels, n = 7) and DKO (GTT, n = 13; ITT, n = 19; insulin plasma levels, n = 8) mice. (b) GTT, ITT, and insulin plasma levels from 12-month-old WT (GTT, n = 9; ITT, n = 10; insulin plasma levels, n = 4 to 7) and DKO (GTT, n = 15; ITT, n = 18; insulin plasma levels, n = 5 to 9) mice. Results are presented as mean ± standard error of the mean. Statistical significance was assessed by two-tailed Student t test; *P < 0.05, **P < 0.01, and ***P < 0.001 between WT and DKO groups.