Table 2.
CGM Intervention and Metrics of Glycemic Control
| Variable | Run-in | 3 mo | 6 mo | 9 mo | 12 mo | 15 mo | 18 mo |
|---|---|---|---|---|---|---|---|
| Dexcom/Medtronic (n/n) | 7/4 | 7/4 | 7/4 | 7/4 | 7/4 | 7/4 | 7/4 |
| Insulin requirement (U·kg−1·d−1) | 0.5 ± 0.1 | — | 0.5 ± 0.0 | — | 0.5 ± 0.0 | — | 0.5 ± 0.0 |
| Mean glucose (mg/dL) | 157 ± 6 | 159 ± 8 | 165 ± 10 | 170 ± 12 | 166 ± 11 | 158 ± 7 | 157 ± 8 |
| Glucose SDa (mg/dL) | 71 ± 5 | 68 ± 6 | 66 ± 4 | 68 ± 6 | 69 ± 6 | 64 ± 5 | 63 ± 4 |
| Time with glucose > 180 mg/dL (%) | 34 ± 4 | 32 ± 5 | 36 ± 5 | 37 ± 6 | 35 ± 5 | 32 ± 4 | 32 ± 5 |
| Time with glucose < 60 mg/dL (%) | 6.5 ± 1.6 | 4.3 ± 1.2 | 4.1 ± 1.0 | 3.6 ± 0.8 | 3.9 ± 0.8 | 4.0 ± 0.7 | 4.0 ± 0.7 |
| Dayb time with glucose < 60 mg/dL (%) | 6.2 ± 1.9 | 3.9 ± 1.1 | 3.5 ± 0.7 | 3.6 ± 0.8 | 3.5 ± 0.7 | 3.9 ± 0.7 | 3.6 ± 0.6 |
| Nocturnalc time with glucose < 60 mg/dL (%) | 6.8 ± 1.6 | 5.7 ± 1.7 | 6.2 ± 2.0 | 4.1 ± 1.6 | 5.1 ± 1.7 | 4.8 ± 1.6 | 5.2 ± 1.7 |
| No. of severe hypoglycemic events per yd | 2.2 ± 0.7 | — | 1.4 ± 0.6 | — | 1.2 ± 0.7 | — | 0.9 ± 0.5 |
Unless otherwise noted, data are mean ± standard error of the mean.
P = 0.07.
Day hours defined as 0600 to 0000.
Nocturnal hours defined as 0000 to 0600.
P < 0.01.