Table 1.
Baseline Clinical and Biochemical Characteristics of Study Participants by Treatment Group
| Characteristic | MCS (n = 10) | Placebo (n = 10) | P Value |
|---|---|---|---|
| Age, mo | 125 ± 4.9 | 126 ± 4.7 | NS |
| Sex (male:female), n | 3:7 | 3:7 | NS |
| Tanner stage ratio (I–II:III–V), n | 7:3 | 6:4 | NS |
| BMI (kg/m2) | 32.1 ± 1.5 | 27.1 ± 1.6 | 0.036 |
| BMI z-score | 2.42 ± 0.08 | 1.99 ± 0.15 | 0.021 |
| WHtR | 0.68 ± 0.02 | 0.63 ± 0.03 | NS |
| VAT per MRI, g | 302 ± 39 | 310 ± 50 | NS |
| SAT per MRI, g | 2550 ± 255 | 1625 ± 280 | 0.03 |
| β-carotene, μg/dL | 10.9 ± 0.01 | 13.8 ± 0.03 | NS |
| Glucose, mg/dL | 82 ± 2.5 | 80 ± 1.8 | NS |
| Insulin, mIU/mL | 23.0 ± 3.1 | 20.3 ± 4.2 | NS |
| HOMA-2 | 2.66 ± 0.36 | 2.59 ± 0.47 | NS |
| Triglycerides, mg/dLa | 89 (69–163) | 75 (48–105) | NS |
| Total adiponectin, μg/dL | 8.68 ± 1.49 | 7.74 ± 1.04 | NS |
| HMW -ADI, µg/dL | 4.39 ± 0.97 | 4.38 ± 0.98 | NS |
| Leptin, µg/L | 40.5 ± 5.7 | 28.9 ± 5.7 | NS |
| Leptin/adiponectin ratio | 7.32 ± 2.6 | 4.93 ± 1.4 | NS |
All values mean ± standard error of the mean except where noted.
Abbreviation: NS, not significant.
a
Median (interquartile range, 25%–75%).