Table 3.
Pairwise Comparisons for Mean Treatment Effects for HOMA-2 and Adipokine Concentrations Between MCS and Placebo Groups
| Variable |
MCS (n
=
8)
|
Placebo (n
=
9)
|
Mean Difference | P Value a | ||||
|---|---|---|---|---|---|---|---|---|
| 0 mo | 3 wk | 6 mo | 0 mo | 3 wk | 6 mo | |||
| HOMA-2 | 2.60 ± 0.4 | 2.26 ± 0.5 | 2.34 ± 0.8 | 2.77 ± 0.4 | 3.86 ± 0.5 | 3.40 ± 0.7 | −1.28 ± 0.7 | 0.084 |
| Total adiponectin, μg/dL | 8.79 ± 0.9 | 7.38 ± 0.9 | 10.36 ± 0.9 | 6.26 ± 0.8 | 6.44 ± 0.9 | 6.50 ± 0.8 | 2.73 ± 0.9 | 0.611 |
| HMW-ADI | 4.65 ± 0.8 | 4.20 ± 0.9 | 7.53 ± 1.1 | 3.35 ± 0.7 | 3.04 ± 0.8 | 2.86 ± 1.1 | 1.63 ± 0.7 | 0.037 |
| HMW/total adiponectin ratio | 0.49 ± 0.09 | 0.53 ± 0.09 | 0.67 ± 0.08 | 0.46 ± 0.08 | 0.41 ± 0.09 | 0.37 ± 0.07 | 0.18 ± 0.06 | 0.005 |
| Leptin, µg/L | 36.6 ± 5.5 | 27.0 ± 7.2 | 34.6 ± 6.8 | 34.8 ± 5.2 | 33.7 ± 6.7 | 30.3 ± 6.4 | −3.13 ± 5.7 | 0.590 |
| Leptin/adiponectin ratio | 6.2 ± 2.1 | 5.9 ± 2.4 | 5.3 ± 2.0 | 7.2 ± 2.0 | 6.4 ± 2.2 | 5.8 ± 1.9 | 0.467 ± 0.6 | 0.476 |
All values presented as mean ± standard error of the mean and adjusted for baseline values, Tanner stage, and BMI z-score.
a
Bonferroni adjusted P value for between-subject treatment effects.