Table 1. Overview of datasets. We provide an overview of the datasets used throughout this study.

Dataset name	Type	Source	Number of samples	Source
HPV-Sim	WGS	Simulated	96	This study
HCC-WGS	WGS	Biological	20	(21)
HCC-RNA	RNA-seq	Biological	6	(22)
TCGA-CESC	WGS and RNA-seq	Biological	68	TCGA