Table 1.
Characteristics of vertically infected neonates admitted to the pediatric ward in the Saint Elisabeth Hospital, Willemstad, Curaçao
| Case 1 | Case 2 | Case 3 | |
|---|---|---|---|
| EGA at maternal CHIKV infection (weeks + days) | 28 + 3 | 39 + 3 | 38 + 5 |
| EGA at delivery (weeks + days) | 35 + 2 | 39 + 3 | 38 + 6 |
| Apgar score 1 minute/5 minutes | 6/7 | 9/10 | 9/9 |
| Sex | Male | Female | Female |
| Birthweight in grams (centiles) | 2535 g (50–90th p) | 2745 g (10–50th p) | 3050 g (10–50th p) |
| First day of symptoms according to DOB | 0 | 5 | 4 |
| Neonatal symptoms | |||
| Fever | No | Yes | No |
| Irritability/pain | Yes | Yes | Yes |
| Skin rash | No | No | Yes |
| Skin bullae | No | No | No |
| Convulsions | Yes | Yes | No |
| Length of hospital stay in days | 1 | 16 | 10 |
| Death | Yes | No | No |
| Neonatal CHIKV serology | |||
| IgM | Positive | Positive | Positive |
| IgG | Positive | Negative | Positive |
| Complementary brain imaging | CT scan | MRI | Not performed |
| Extensive bleeding | White matter lesions T0 | – | |
| Cerebrospinal fluid | Not taken | Normal | Not taken |
CHIKV = Chikungunya virus; CT scan = computed tomography scan; DOB = date of birth; EGA = estimated gestational age; MRI = magnetic resonance imaging.