Table 3.
Multivariable-adjusted logistic regression for mortality of 198 adult patients with acute melioidosis
| Variables | Patients who survived, n (%) | Patients who died, n (%) | Crude OR (95% CI) | Adjusted OR (95% CI) | P-value | |
|---|---|---|---|---|---|---|
| All patients | N = 147 | N = 51 | ||||
| Seropositive (indirect hemagglutination assay ≥ 1:80) | 114/147 (78%) | 29/51 (57%) | 0.4 (0.2–0.8)* | 0.5 (0.2–1.0) | 0.05 | |
| Age ≥ 45 years | 115/147 (78%) | 42/51 (82%) | 1.3 (0.6–2.9) | 0.7 (0.3–1.9) | 0.56 | |
| Diabetes | 101/147 (69%) | 32/51 (63%) | 0.8 (0.4–1.5) | 0.8 (0.4–1.7) | 0.61 | |
| Preexisting renal disease | 20/147 (14%) | 15/51 (29%) | 2.6 (1.2–5.7)* | 3.1 (1.3–7.4) | 0.01 | |
| Neutrophil count/µL12 | 0.001 | |||||
| > 4,000–8,000† | 52/147 (35%) | 3/51 (6%) | 1.0 | 1.0 | ||
| ≤ 4,000 | 15/147 (10%) | 5/51 (10%) | 5.8 (1.2–27.0)* | 6.1 (1.2–30.3) | ||
| > 8,000–12,000 | 44/147 (30%) | 22/51 (43%) | 8.7 (2.4–30.9)* | 10.9 (2.9–41.4) | ||
| ≥ 12,000 | 36/147 (24%) | 21/51 (41%) | 10.1 (2.8–36.4)* | 11.0 (2.9–42.5) |
CI = confidence interval; OR = odds ratio.
*
P < 0.05.
†
Normal neutrophil range.