Table 2. Univariate correlation analysis of median ddcfDNA baseline values of the entire study cohort with recipient, donor or transplantation characteristics.
Recipient characteristics (at transplantation) | Correlation coefficient | Adjusted p-value |
Study Center | N/A | 1.00 |
Gender | N/A | 1.00 |
Age | -0.057 | 1.00 |
BMI | -0.135 | 1.00 |
Residual diuresis (0 ml/day, ≤500 ml/day, >500 ml/day) | N/A | 1.00 |
Primary renal disease (glomerular/chronic interstitial nephritis/cystic disease/renal vascular disease/diabetes/other) | N/A | 1.00 |
PRA (%) | 0.282 | 0.078 |
Presence donor specific antibodies | N/A | 1.00 |
Donor kidney in situ from previous transplantation | N/A | 1.00 |
Diabetes Mellitus Type II | N/A | 1.00 |
Current smoking | N/A | 1.00 |
Obesitas (BMI ≥ 30 kg/m) | N/A | 1.00 |
Chronic inflammatory diseases | N/A | 1.00 |
Donor and transplantation characteristics | Correlation coefficient | Adjusted p-value |
Age | 0.004 | 1.00 |
Type (living/deceased) | N/A | 1.00 |
BMI | 0.127 | 1.00 |
BMI Difference recipient-donor | -0.174 | 1.00 |
Number of HLA mismatches in HLA A and B | -0.086 | 1.00 |
Number of HLA mismatches in HLA DR | -0.143 | 1.00 |
Cold ischemia time | 0.088 | 1.00 |
2nd warm ischemia time | 0.137 | 1.00 |
Induction therapy (IL2-RA, ATG) | N/A | 1.00 |
BMI: Body mass index; PRA: panel reactive antibodies; HLA: Human leukocyte antigen; IL2-RA: Interleukin-2 receptor antagonist; ATG: Anti-thymocyte globulin; N/A: not applicable. Spearman correlation coefficients are shown for continuous variables. Categorical variables were tested using an analysis of variance (ANOVA) to test difference between the different groups (only p-value reported). p-values are adjusted according to a Bonferroni correction for multiple testing.