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. 2018 Dec 6;13(12):e0208207. doi: 10.1371/journal.pone.0208207

Table 2. Univariate correlation analysis of median ddcfDNA baseline values of the entire study cohort with recipient, donor or transplantation characteristics.

Recipient characteristics (at transplantation) Correlation coefficient Adjusted p-value
Study Center N/A 1.00
Gender N/A 1.00
Age -0.057 1.00
BMI -0.135 1.00
Residual diuresis (0 ml/day, ≤500 ml/day, >500 ml/day) N/A 1.00
Primary renal disease (glomerular/chronic interstitial nephritis/cystic disease/renal vascular disease/diabetes/other) N/A 1.00
PRA (%) 0.282 0.078
Presence donor specific antibodies N/A 1.00
Donor kidney in situ from previous transplantation N/A 1.00
Diabetes Mellitus Type II N/A 1.00
Current smoking N/A 1.00
Obesitas (BMI ≥ 30 kg/m) N/A 1.00
Chronic inflammatory diseases N/A 1.00
Donor and transplantation characteristics Correlation coefficient Adjusted p-value
Age 0.004 1.00
Type (living/deceased) N/A 1.00
BMI 0.127 1.00
BMI Difference recipient-donor -0.174 1.00
Number of HLA mismatches in HLA A and B -0.086 1.00
Number of HLA mismatches in HLA DR -0.143 1.00
Cold ischemia time 0.088 1.00
2nd warm ischemia time 0.137 1.00
Induction therapy (IL2-RA, ATG) N/A 1.00

BMI: Body mass index; PRA: panel reactive antibodies; HLA: Human leukocyte antigen; IL2-RA: Interleukin-2 receptor antagonist; ATG: Anti-thymocyte globulin; N/A: not applicable. Spearman correlation coefficients are shown for continuous variables. Categorical variables were tested using an analysis of variance (ANOVA) to test difference between the different groups (only p-value reported). p-values are adjusted according to a Bonferroni correction for multiple testing.