Table 1. Demographic and clinical characteristics of subjects according to hyperfiltration status after adjusting for age, sex, and body weight.
Parameter | Hyperfiltration (-) | Hyperfiltration (+) | |
---|---|---|---|
N (%) | 15109 (94.9) | 809(5.1) | |
Age, years | 50.08±16.07 | 46.67±16.43 | <0.001 |
Male gender, (% | 42.1 | 41.8 | 0.854 |
BMI, kg/m2 | 23.69±0.01 | 24.03±0.05 | <0.001 |
Waist circumference, cm | 80.78±0.04 | 82.26±0.16 | <0.001 |
Current smoking, % | 18.7 | 23.8 | <0.001 |
Alcohol consumption, % | 48.2 | 52.8 | 0.018 |
SBP, mmHg | 118.2±0.1 | 119.9±0.5 | 0.001 |
DBP, mmHg | 75.4±0.1 | 75.1±0.3 | 0.463 |
Antihypertensive medication, % | 18.9 | 13.8 | <0.001 |
HbA1c, % | 5.772±0.006 | 5.843±0.025 | 0.006 |
Fasting plasma glucose, mg/dL | 97.97±0.16 | 100.49±0.69 | <0.001 |
Diabetes mellitus, % | 9.7 | 10.5 | 0.401 |
Diabetes duration, years | 8.30±7.52 | 7.19±7.26 | 0.240 |
Antidiabetic medication, % | 6.17 | 7.05 | 0.314 |
Insulin therapy, % | 0.51 | 0.49 | 0.952 |
Total cholesterol, mg/dL | 189.6±0.3 | 188.5±1.2 | 0.391 |
Triglyceride, mg/dL | 129.9±0.8 | 146.8±3.4 | <0.001 |
HDL-cholesterol, mg/dL | 52.72±0.10 | 53.17±0.41 | 0.291 |
Lipid lowering medication, % | 7.3 | 3.3 | <0.001 |
Serum creatinine, mg/dL | 0.824±0.001 | 0.622±0.003 | <0.001 |
eGFR, ml/min/1.73 m2 | 94.49±0.08 | 110.47±0.35 | <0.001 |
Urine creatinine, g/dL | 1.543±0.062 | 1.278±0.267 | <0.001 |
Urine albumin, mg/dL | 0.136±0.003 | 0.163±0.012 | 0.036 |
ACR, mg/g | 0.951±0.018 | 1.399±0.079 | <0.001 |
Energy intake, kcal | 2019±7 | 2094±29 | 0.010 |
Water intake, g | 1064±5 | 1089±23 | 0.293 |
Protein intake, g | 71.67±0.32 | 73.43±1.38 | 0.215 |
Fat intake, g | 42.18±0.26 | 42.81±1.12 | 0.580 |
Carbohydrate intake, g | 319.5±1.0 | 326.3±4.5 | 0.215 |
Sodium intake, mg | 4487±25 | 4579±110 | 0.421 |
BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HbA1c, glycated hemoglobin; HDL, high-density lipoprotein; eGFR, estimated glomerular filtration rate; ACR, albumin creation ratio