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. 2018 Dec 6;13(12):e0208316. doi: 10.1371/journal.pone.0208316

Fig 7. Analysis of the gene expression of Nrf2 and Keap1 in reticulocytes of BTI patients (n = 15) and healthy individuals (n = 16).

Fig 7

RT-qPCR analyzes showed an increase in the gene expression of Nrf2 (approx. 3 fold change) and Keap1 (approx. 2 fold change) in the reticulocytes of the BTI group when compared to the control group. Primers used for these analyzes are described in S1 Table. mRNA abundance for each gene was normalized to Bac as the endogenous reference. Results are presented as mean and standard error (± SEM). Statistical significance: *p < 0.05, **p < 0.001.