Table 2.
Four haplotypes are associated with increased or decreased susceptibility of PF
Haplotype | SNP 1 | SNP 2 | SNP 3 | Haplotype | PF F (%) | CTR F (%) | OR | P |
---|---|---|---|---|---|---|---|---|
H1 | rs1325158 | rs4806527 | rs2075731 | TGC | 6·3 | 2·5 | 2·56 | 0·023 |
LILRP2 downstream | LILRP2 downstream | KIR3DL3 | ||||||
H2 | rs4806768 | rs61737870 | TC | 36·6 | 44·3 | 0·73 | 0·030 | |
LAIR2 | LAIR2 | |||||||
H3 | rs1654644 | rs11665986 | TT | 23·2 | 18·3 | 1·46 | 0·037 | |
KIR3DL2 | FCAR upstream | |||||||
H4 | rs10423364 | rs1061680 | rs61739173 | ACA | 5·2 | 8·1 | 0·58 | 0·041 |
LILRB1 upstream | LILRB1 | LILRB1 |
CTR, controls samples; F, frequency; H, haplotype; OR, odds ratio; PF, pemphigus foliaceus patients; SNP, single nucleotide polymorphism.