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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Pediatr Crit Care Med. 2018 Dec;19(12):1137–1145. doi: 10.1097/PCC.0000000000001742

Table 4:

Comparison of Medical Examiner and Non-Medical Examiner Autopsies

Category Variable Medical Examiner Autopsies (n=47) Non-Medical Examiner Autopsies (n=53) Significance Level
Socio-Demographics
Gender (%) 0.661
Male 26 (49.1) 27 (50.9)
Female 21 (44.7) 26 (55.3)
Age, median [IQR] 1.1 [0.3–8.6] 0.8 [0.0–5.9] 0.172
Age category (%) 0.0033
0 to <14 days 0 (0.0) 13 (100.0)
14 days to <1 month 1 (50.0) 1 (50.0)
1 month to <12 months 20 (55.6) 16 (44.4)
12 months to <60 months 11 (61.1) 7 (38.9)
60 months to < 144 months 10 (45.5) 12 (54.5)
>144 months 5 (55.6) 4 (44.4)
Payer Type 0.123,4
Government 29 (43.3) 38 (56.7)
Commercial 13 (54.2) 11 (45.8)
Other 3 (100.0) 0 (0.0)
Missing 2 (33.3) 4 (66.7)
Baseline Function
Baseline FSS, median [IQR] 6 [6–6] 6 [6–9] <0.0012
Underlying Conditions
Cancer Diagnosis: Present 1 (20.0) 4 (80.0) 0.373
                                    Absent 46 (48.4) 49 (51.6)
Congenital Heart Disease: Present 2 (6.1) 31 (93.9) <0.0011
                                                 Absent 45 (67.2) 22 (32.8)
Events prior to admission
Trauma: Yes 14 (100.0) 0 (0.0) <0.0011
                 No 33 (38.4) 53 (61.6)
Cardiac Arrest: Yes 29 (85.3) 5 (14.7) <0.0011
                            No 18 (27.3) 48 (72.7)
Admission Status
Elective (scheduled) 4 (23.5) 13 (76.5) 0.0331
Emergent (unscheduled) 43 (51.8) 40 (48.2)
Admission Source 0.0051
Post-Operative, n (%) 6 (28.6) 15 (71.4)
Inpatient, n (%) 5 (23.8) 16 (76.2)
Direct Admission from Referral Hospital, n (%) 22 (61.1) 14 (38.9)
Emergency Department, n (%) 14 (63.6) 8 (36.4)
Primary System of Dysfunction <0.0013
Respiratory, n (%) 8 (36.4) 14 (63.6)
Cardiovascular, n (%) 22 (44.9) 27 (55.1)
Cancer, n (%) 0 (0.0) 2 (100.0)
Neurologic, n (%) 16 (88.9) 2 (11.1)
Other, n (%) 1 (11.1) 8 (88.9)
Severity of Illness
PRISM Score, median [IQR] 23 [17–31] 11 [5–19] <0.0012
Resource Use
PICU LOS, median [IQR] 2.8 [1.1–6.3] 4.2 [1.4–22.0] 0.112
Hospital LOS, median [IQR] 2.8 [1.1–6.8] 8.2 [2.4–42.0] 0.0032
ICU Therapies
Mechanical Ventilation, n (%) 46 (97.9) 49 (92.5) 0.373
Vasoactive Agent Infusions, n (%) 40 (85.1) 48 (90.6) 0.401
Antibiotics, n (%) 37 (78.7) 49 (92.5) 0.0481
Steroids, n (%) 16 (34.0) 32 (60.4) 0.0091
Location of Death 0.253
PICU, n (%) 46 (97.9) 49 (92.5)
Hospital General Care, n (%) 1 (2.1) 1 (1.9)
Other, n (%) 0 (0.0) 3 (5.7)
1.

Chi-squared

2.

Wilcoxon Rank Sum

3.

Fisher’s Exact

4.

Missing variables excluded (2 patients with ME autopsies and 4 patients with non-ME autopsies)

IQR: Interquartile range; FSS: Functional Status Scale; PRISM: Pediatric Risk of Mortality

PICU: Pediatric Intensive Care Unit; LOS: Length of stay