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. Author manuscript; available in PMC: 2019 Dec 15.
Published in final edited form as: J Comp Neurol. 2018 Nov 16;526(18):2921–2936. doi: 10.1002/cne.24484

Figure 8.

Figure 8

Scatter plots showing that colocalization of tau in activated microglia (PHF-1/Iba1-ir microglia density, MGv, mm3) was associated with increased intermediate morphology in the neocortex (a; R2 = 0.24, p = 0.03). Aβ42 plaque volume (%) in the neocortex (b; R2 = 0.25, p = 0.02) and hippocampus (c; R2 = 0.18, p = 0.04) correlated with increased activation of microglia (Iba1-ir microglia density, mm3) and intermediate morphology (d; R2 = 0.35, p = 0.03) in the hippocampus. Aβ42 vessel volume also was associated with greater activated microglial density in the hippocampus (e; R2 = 0.19, p = 0.03).