Table 2:

Standardized Mortality Ratios (SMR) for DM1-affected Relatives by their Reported DM1-status

		DM1-Unaffected			DM1-Affected			DM1-Unknown
		O	E	SMR (95% CI)	O	E	SMR (95% CI)	O	E	SMR (95% CI)
Parents	US	29	38.27	0.76 (0.56, 1.02)	55	32.32	1.70 (1.47, 1.97)	85	64.47	1.32 (1.17, 1.48)
	UK	25	23.02	1.09 (0.81, 1.46)	57	21.05	2.71 (2.38, 3.08)	45	31.59	1.42 (1.20, 1.69)
	Total	54	61.29	0.88 (0.71, 1.09)	112	53.36	2.10 (1.90, 2.31)	130	96.06	1.35 (1.23, 1.49)
Siblings	US	16	21.03	0.76 (0.46, 1.26)	32	12.14	2.64 (2.16, 3.22)	15	3.88	3.87 (3.06, 4.90)
	UK	4	4.64	0.86 (0.32, 2.34)	20	4.58	4.37 (3.58, 5.34)	18	2.95	6.11 (5.18, 7.21)
	Total	20	25.67	0.78 (0.50, 1.22)	52	16.72	3.11 (2.69, 3.59)	33	6.82	4.84 (4.21, 5.56)
Offspring	US	0	2.27	-	6	2.22	2.70 (1.67, 4.36)	1	1.01	0.99 (0.14, 6.90)
	UK	0	0.59	-	11	0.85	12.93 (10.98, 15.22)	3	0.38	7.87 (5.27, 11.76)
	Total	0	2.86	-	17	3.07	5.53 (4.53, 6.75)	4	1.39	2.87 (1.62, 5.08)
Total		74	89.82	0.82 (0.67, 1.01)	181	73.16	2.47 (2.29, 2.67)	167	104.27	1.60 (1.48, 1.74)

Abbreviations: O (observed), E (expected), SMR (standardized mortality ratio), CI (confidence interval)