Table 3:
Results of multivariable logistic regression models for probability of cancer in all relatives combined (a) and stratified by their relationship to the reporting respondent (b-d)
| Covariate |
a) All 1st-Degree Relatives |
b) Parents | c) Siblings | d) Offspring | |||||
|---|---|---|---|---|---|---|---|---|---|
|
Odds Ratio |
95% CI |
Odds Ratio |
95% CI |
Odds Ratio |
95% CI |
Odds Ratio |
95% CI | ||
| US vs. UK | 1.42 | 1.06-1.91 | 1.09 | 0.77, 1.54 | 1.61 | 0.90, 2.90 |
2.51 | 0.83, 7.55 | |
|
Proband Cancer (Yes vs. No) |
1.95 | 1.39, 2.73 | 2.65 | 1.76, 4.01 | 1.43 | 0.80, 2.54 |
0.77 | 0.26, 2.28 | |
|
DM Status (vs. Unaffected) |
Unknown | 1.26 | (0.90, 1.75) | 1.15 | 0.77, 1.72 | 2.59 | 1.37, 4.88 |
2.68 | 0.81, 8.86 |
| Affected | 1.28 | (0.94, 1.75) | 1.11 | 0.72, 1.69 | 1.23 | 0.72, 2.12 |
1.71 | 0.53, 5.57 | |
| Male vs. female | 0.96 | (0.74, 1.24) | 1.44 | 1.03, 2.01 | 0.66 | 0.41, 1.08 |
0.36 | 0.13, 0.98 | |