Table 1.
AP group (n = 41) | P group (n = 44) | P value | |
---|---|---|---|
Age (yr) | 52 ± 12 | 52 ± 12 | 0.887 |
Weight (kg) | 60 ± 9 | 62 ± 9 | 0.337 |
History of PONV | 5 (12%) | 4 (9%) | 0.733 |
History of motion sickness | 17 (41%) | 13 (30%) | 0.251 |
Smoker | 2 (5%) | 6 (14%) | 0.268 |
Type of surgery | 0.780 | ||
Major orthopedic operation | 35 (85%) | 35 (80%) | |
Thyroidectomy | 2 (5%) | 2 (5%) | |
Laparoscopic hysterectomy | 1 (2%) | 3 (7%) | |
Laparoscopic cholecystectomy | 3 (7%) | 4 (9%) | |
Duration of surgery (min) | 86 ± 56 | 89 ± 60 | 0.755 |
Duration of anesthesia (min) | 129 ± 56 | 132 ± 66 | 0.831 |
Values are expressed as mean ± SD or number of patients (%). AP group: 80 mg aprepitant per oral plus 0.075 mg intravenous palonosetron, P group: 0.075 mg intravenous palonosetron alone. PONV: postoperative nausea and vomiting.