Table 2.
Incidence of Nausea and Vomiting, and Use of Rescue Antiemetic Medication during the First 24 Hours after Surgery
| AP group (n = 41) | P group (n = 44) | P value | |
|---|---|---|---|
| 0–6 h | |||
| Nausea | 20 (49%) | 20 (45%) | 0.829 |
| Vomiting | 1 (2%) | 3 (7%) | 0.617 |
| PONV | 20 (49%) | 20 (45%) | 0.829 |
| Rescue antiemetics | 11 (27%) | 11 (25%) | 1.000 |
| 6–24 h | |||
| Nausea | 7 (17%) | 12 (27%) | 0.305 |
| Vomiting | 0 (0%) | 3 (7%) | 0.242 |
| PONV | 7 (17%) | 14 (32%) | 0.137 |
| Rescue antiemetics | 2 (5%) | 5 (11%) | 0.435 |
| 0–24 h | |||
| Nausea | 22 (54%) | 21 (48%) | 0.666 |
| Vomiting | 1 (2%) | 6 (14%) | 0.111 |
| PONV | 22 (54%) | 23 (52%) | 1.000 |
| Rescue antiemetics | 12 (29%) | 14 (32%) | 0.818 |
Values are expressed as number of patients (%). AP group: 80 mg aprepitant per oral plus 0.075 mg intravenous palonosetron, P group: 0.075 mg intravenous palonosetron alone. PONV: postoperative nausea and vomiting.