Table 2.

Ventilation parameters through the protocol.

	Baseline	Insult	p	TLV-1 min	TLV-30 min	TLV-120 min	p
Vt (ml/kg)	6.6 ± 1.3	6.2 ± 2.4	0.5	12.4 ± 0.2	13.6 ± 1.0∗	14.6 ± 1.3∗,†	0.03
RR (/min)	49 ± 13	51 ± 6.1	0.3	6.7 ± 0.6	9.3 ± 0.7∗	8.8 ± 0.5∗	0.002
PIP/EIPP (cmH2O)	14.5 ± 1.7	18.3 ± 2.3	0.04	17.0 ± 2.6	14.7 ± 2.3∗	11.8 ± 3.2∗,†	0.002
PEEP/EEPP (cmH2O)	5.1 ± 0.6	6.6 ± 2.2	0.02	12.2 ± 2.0	4.2 ± 3.0∗	0.7 ± 4.1∗,†	0.001

Gas ventilation parameters, at baseline and after the insult, are reported for 8 animals and compared using a Wilcoxon signed-rank test. Liquid tidal volume (Vt), respiratory rate (RR), end-expiratory pause pressure (EEPP) could only be recorded in 7 subjects and end-inspiratory pause pressure (EIPP) in 6 during total liquid ventilation (TLV) due to technical problems. Differences for total liquid ventilation parameters were assessed with a Friedman test for repeated measures followed by a Wilcoxon signed-rank test (^∗if p < 0.05 when compared to TVL-1 min value, ^†if p < 0.05 when compared to TVL-30 min value). Data are presented as mean ± SD. PIP, peak inspiratory pressure during gas ventilation. PEEP, positive end-expiratory pressure during gas ventilation.