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. 2018 Nov 30;9:1400. doi: 10.3389/fphar.2018.01400

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Copyright © 2018 Ohsawa, Maruoka, Inami, Iwaki, Murakami and Ishikura.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of Ninjin’yoeito (NYT) on the alterations in (A) body weight, (B) gastrocnemius skeletal muscle weight, and (C) epididymal adipose tissue weight in mice with cancer cachexia. NYT was administered once a daily from 1 h before B16BF6 melanoma implantation and continued for 14 days. Each column represents the mean with SEM from 10 mice. ^∗P < 0.05 vs. water-treated no-cancer group. ^#P < 0.05 vs. water-treated cancer group.