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. 2018 Nov 30;9:2983. doi: 10.3389/fmicb.2018.02983

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Copyright © 2018 Panteleev, Bolosov, Kalashnikov, Kokryakov, Shamova, Emelianova, Balandin and Ovchinnikova.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of individual goat cathelicidins ChMAP-28 or mini-ChBac7.5Nα, their synergistic combination, and polymyxin B at different concentrations including sub-inhibitory MICs on planktonic cell growth and biofilm formation of E. coli clinical isolate. Biofilm formation was assessed by the colorimetric crystal violet-based technique. The results are expressed as percentage of the planktonic growth or the formed biofilm by reference to an untreated control taken as 100%. Data are the mean ± SD of at least three independent experiments performed in triplicate. ^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001 significantly different compared to the control.