Table 1.
Parasite development in Anopheles stephensi infected with Plasmodium berghei lines LAP4/GFP, LAP3/GFP and LAP3-KO.
| Experiment | Parasite line | Mean ± S.E.M. oocyst number 10 dpia (n)b |
Mean midgut sporozoite number 10 dpi (n) |
Mean midgut sporozoite number 14 dpi (n) |
Mean hemocoel sporozoite number 10 dpi (n) |
Mean hemocoel sporozoite number 14 dpi (n) |
Mean hemocoel sporozoite number 21 dpi (n) |
Mean salivary gland sporozoite number 21 dpi (n) |
|---|---|---|---|---|---|---|---|---|
| 1 | LAP3/GFP | 33 ± 15 (10) | 0 (10) | 3200 (10) | n/ac | n/a | n/a | n/a |
| LAP4/GFP clone 1 | 29 ± 20 (10) | 3500 (10) | 2200 (10) | n/a | n/a | n/a | n/a | |
| 2 | LAP3/GFP | 45 ± 19 (10) | 600 (10) | 22,500 (10) | n/a | n/a | n/a | n/a |
| LAP4/GFP clone 2 | 38 ± 21 (10) | 8400 (10) | 6750 (10) | n/a | n/a | n/a | n/a | |
| 3 | LAP3/GFP | 57 ± 13 (20) | n/a | n/a | 0 (20) | 1066 (20) | 830 (20) | 2900 (20) |
| LAP4/GFP clone 2 | 70 ± 16 (20) | n/a | n/a | 0 (20) | 118 (20) | 131 (18) | 125 (20) | |
| 4 | LAP3/GFP | 74 ± 21 (20) | n/a | n/a | n/a | n/a | n/a | 4530 (35) |
| LAP4/GFP clone 1 | 76 ± 25 (20) | n/a | n/a | n/a | n/a | n/a | 145 (40) | |
| LAP3-KO | 81 ± 26 (20) | n/a | n/a | n/a | n/a | n/a | 0 (38) |
a
dpi, days p.i.
b
n, number of mosquitoes dissected.
c
n/a, not assessed.