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. 2018 Nov 30;9:2932. doi: 10.3389/fmicb.2018.02932

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Copyright © 2018 Bruhn, Schindler, Kemter, Wiley, Chase, Koroleva, Palacios, Sozhamannan and Waldminghaus.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Single nucleotide polymorphism (SNP) analysis of replication origins of V. cholerae strains NSCV1 and NSCV2 in comparison to N16961. Genes are indicated as black arrows, RctB binding iterons in dark gray (11 mer iteron) and light gray (12 mer iteron), DnaA boxes in blue and SNPs as stars. The figure is not drawn to scale. Reference sequence: N16961 (Accession # NC002505 and NC002506). Apart from the highlighted SNPs, the sequences are identical. (A) Alignment of ori1. (B) Alignment of ori2.