Table 10.
Univariate analysis of risk factors for GP resistance in SqCC.
| Variable | PD+SD (n,%) | PR+CR (n,%) | P value |
|---|---|---|---|
| Gender | |||
| Female | 10 (75) | 2 (25) | 0.14 |
| Male | 41 (61.194) | 26 (38.806) | |
| Age (yr) | |||
| ≥58.5 | 16 (50) | 16 (50) | 0.026 |
| <58.5 | 35 (72.34) | 12 (27.66) | |
| TNM stage | |||
| IIIA | 7 (58.333) | 5 (41.667) | 0.757 |
| IIIB | 16 (61.538) | 10 (38.462) | |
| IV | 28 (65.854) | 13 (34.146) | |
| Smoking | |||
| Never smoker | 17 (76.19) | 4 (23.81) | 0.067 |
| Current or former smoker | 34 (58.621) | 24 (41.379) | |
| PLT (109/L) | |||
| <229.5 | 18 (51.429) | 17 (48.571) | 0.03 |
| ≥229.5 | 33 (72.727) | 11 (27.273) | |
| MPV (fl) | |||
| <9.3 | 10 (45.455) | 12 (54.545) | 0.027 |
| ≥9.3 | 41 (70.175) | 16 (29.825) | |
| PCT (%) | |||
| <0.235 | 17 (45.946) | 20 (54.054) | 0.001 |
| ≥0.235 | 33 (78.571) | 9 (21.429) | |
| PDW (%) | |||
| ≥14.95 | 13 (43.333) | 17 (56.667) | 0.002 |
| <14.95 | 38 (75.51) | 11 (24.49) | |
| CA125 (U/mL) | |||
| <16.9 | 14 (44.828) | 16 (55.172) | 0.005 |
| ≥16.9 | 38 (74) | 12 (26) | |
| CA125 (U/mL)-standard | |||
| <35 | 30 (57.692) | 22 (42.308) | 0.077 |
| ≥35 | 21 (77.778) | 6 (22.222) | |
PD – progressive disease; SD – stable disease; PR – partial responses; CR – complete response; PLC – platelet count; MPV – mean platelet volume; PDW – platelet distribution width; PCT – plateletcrit.