Gastric cancer cell lines have different sensitivity to DDP treatment.
(A) Cell viability of SGC7901 and SGC7901/DDP cells, cells were treated with fold diluted DDP. Data were expressed as mean ± SD, n = 4. (B) Cell viability of indicated gastric tumor cells, cells were treated with fold diluted DDP after transfection of S1PR1 overexpression or empty vector. Data were expressed as mean ± SD, n = 4. (C) The correlation of S1PR1 and STAT3 transcriptional levels in patients with a progressive disease outcome. (D) The correlation of S1PR1 and STAT3 transcriptional levels in patients with a complete remission/response outcome.