TABLE 1. Prevalence of nutritional deficiencies associated with calcium metabolism in patients submitted to Roux-en-Y gastric bypass over a 10-year period.
| Biochemical tests | Time | ||||||||
| Pre-op n (%) | 3 months n (%) | 6 months n (%) | 12 months n (%) | 24 months n (%) | 48 months n (%) | 72 months n (%) | 96 months n (%) | 120 months n (%) | |
| Serum calcium * (p=0.1083) | |||||||||
| Sufficient | 103 (97.17) | 89 (90.82) | 60 (89.55) | 101 (93.52) | 92 (92.93) | 78 (87.64) | 61 (93.85) | 38 (88.37) | 36 (97.3) |
| Deficient | 3 (2.83) | 9 (9.18) | 7 (10.45) | 7 (6.48) | 7 (7.07) | 11 (12.36) | 4 (6.15) | 5 (11.63) | 1 (2.7) |
| Ionized calcium * (p=0.5995) | |||||||||
| Sufficient | 54 (85.71) | 68 (86.08) | 53 (92.98) | 86 (89.58) | 73 (86.90) | 69 (84.15) | 53 (85.48) | 37 (90.24) | 28 (87.5) |
| Deficient | 9 (14.29) | 11 (13.92) | 4 (7.02) | 10 (10.42) | 11 (13.10) | 13 (15.85) | 9 (14.52) | 4 (9.76) | 4 (12.5) |
| Parathormone * (p=0.0059) | |||||||||
| Normal | 67 (90.54) | 66 (86.84) | 43 (81.13) | 76 (79.79) | 69 (77.53) | 67 (72.83) | 44 (67.69) | 27 (65.85) | 18 (58.06) |
| High | 7 (9.46) | 10 (13.16) | 10 (18.87) | 19 (20.21) | 20 (22.47) | 26 (27.17) | 21 (32.31) | 14 (34.15) | 13 (41.94) |
| Vitamin D * (p=0.0829) | |||||||||
| Sufficient | ** | 18 (48.65) | 10 (47.62) | 18 (42.86) | 21 (38.89) | 14 (31.82) | 17 (41.46) | 8 (23.53) | 6 (17.14) |
| Deficient | ** | 19 (51.35) | 11 (52.38) | 24 (57.14) | 33 (61.11) | 30 (68.18) | 24 (58.54) | 26 (76.47) | 29 (82.86) |
Time=follow-up time in months; Pre-op=preoperative; patients with vitamin D insufficiency and deficiency were grouped together and considered deficient;
*Generalized estimating equations (GEE) using a significance level of 5%;
** pre-operative assessment not included because most patients had incomplete data, preventing analysis.