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. 2018 Oct 29;10(12):e9091. doi: 10.15252/emmm.201809091

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© 2018 The Authors. Published under the terms of the CC BY 4.0 license

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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A–F
Changed metabolic pathways in blood of IOSCA (A), MIRAS (B), PEO (C), MELAS/MIDD (D), IBM (E) and NMD (F) patients.

G, H
Changed metabolic pathways in muscle of PEO (G) and MIRAS (H) patients.

Data information: Top 10 pathways with ≥ 10% of detected metabolites per pathway are shown. *5% metabolite coverage in the pathway. bio., biosynthesis; deg., degradation; metab., metabolism. See Dataset EV3 for raw data.