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. 2018 Oct 16;37:471–482. doi: 10.1016/j.ebiom.2018.10.009

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© 2018 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 2 — The strongest connected SNP-fALFF-GM component identified by three-way para-ICA. A: scatterplots of pair-wise correlation among the linked SNP-fALFF-GM pattern of SZ (red dot) and HC (blue dot) in cohort 1 after regressing diagnosis. B: group difference between SZ (red dot) and HC (blue dot) revealed by two sample t-test in each modality of cohort 1. C: the spatial maps visualized at |Z| > 2 for the imaging components and Manhattan plot for the SNP component. D: significant Gene Ontology analysis results revealed from 75 high-ranking genes, highlighting pathways like neuron development, synapse organization and axon pathways.