Table 1.
Variable | Pseudo-F | p(perm) | res.df |
---|---|---|---|
Leptin | 3.3 | 0.001 | 30 |
Insulin | 1.8 | 0.015 | 30 |
Glucose | 0.69 | 0.94 | 30 |
Triglycerides | 4.3 | 0.001 | 30 |
Fat mass | 4.6 | 0.001 | 30 |
Change in body weight | 3.2 | 0.002 | 30 |
Distance run | 1.4 | 0.11 | 30 |
Distance based linear modeling (DistLM) was performed using a Bray-Curtis resemblance matrix of the overall gut microbiome composition at the operational taxonomic unit level with metabolic parameters: plasma leptin, insulin, triglyceride and blood glucose concentrations, fat mass, and change in body weight over the experiment as predictor variables. Fat mass was measured as the sum of retroperitoneal, visceral and inguinal fat pads. Distance run represented average kilometers run per day by each rat. A forward-stepping selection procedure and Akaike Information Criterion selection criterion was used. Pseudo-F and p-values were obtained using 999 permutations (perm) and bold values indicate significance, p ≤ 0.05.
res.df = residual degrees of freedom.