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. 2018 Nov 16;10(12):e8861. doi: 10.15252/emmm.201808861

Figure 2. Allogenic contribution and rescue RPEs in the E44 chimeric fetus.

Figure 2

  • A
    Representative microscopic appearances of the retina and RPE cells (arrowhead) of a chimeric, a WT, and a Mut fetus at the same gestational age by H&E staining. WT, Bama WT fetus. Mut, Bama MITF L247S/L247S fetus. NW‐2, the chimeric fetus. Scale bars, 100 μm.
  • B
    Representative immunofluorescence images showed the expression of multiple RPE markers Pax6, MITF, and Bestrophin in the chimeric fetuses. Blue, Hoechst 33342. WT, Bama WT fetus as positive control. NW‐2, the chimeric fetus. MITF L247S/L247S fetus as negative control. Scale bars, 50 μm.

Source data are available online for this figure.