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. 2018 Oct 9;15(10):1255–1267. doi: 10.1080/15476286.2018.1526541

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© 2018 The Author(s). Published by Taylor & Francis.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 6. — Amino acid side chains in the proposed PPARγ-interacting peptide are largely inaccessible. A) Surface rendering of NOCT 120–431 (6BT1; 1.48 Å resolution) [71]. The PPARγ-interacting peptide is highlighted in yellow and the active site is colored in red. One Mg²⁺ ion is coordinated in the active site. B) Magnified view of putative PPARγ-interacting peptide with solvent-accessible amino acid side chains highlighted in orange. C) Cartoon diagram view of the PPARγ-interacting peptide with solvent-exposed amino acid side chains colored in orange.