Table 3.
SS recognition in different mutants |
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Gene | Splice sites | Sequence | rbm-5(n5119) | rbm-5(n5132) | uaf-1(n4588) | rbm-5(n5119); uaf-1(n4588) | rbm-5(n5132); uaf-1(n4588) |
Alt 3ʹ SS gtag | |||||||
mbk-2 | 3ʹ SS | cttgtag | WT | WT | Up | Suppressed | Suppressed |
abt-5 | 3ʹ SS | attgtag | WT | WT | Down | Suppressed | Suppressed |
papl-1 | 3ʹ SS | tttgtag | WT | WT | Down | Suppressed | Suppressed |
F13E6.2 | 3ʹ SS | tttgtag | WT | WT | Down | Suppressed | Suppressed |
gcy-11 | 3ʹ SS | tttgtag | WT | WT | Down | Suppressed | Suppressed |
T26H5.8 | 3ʹ SS | attgtag | WT | WT | Down | No effect | No effect |
Y47H9C.1 | 3ʹ SS | attgtag | WT | WT | Up | No effect | No effect |
pgp-8 | 3ʹ SS | tttgtag | WT | WT | Down | Enhanced | Enhanced |
Alt 3ʹ SS ttag | |||||||
flp-1 | 3ʹ SS | cttttag | WT | WT | Up | No effect | No effect |
str-47 | 3ʹ SS | aatttag | WT | WT | Down | No effect | No effect |
T09F5.20 | 3ʹ SS | aatttag | WT | WT | WT | Synthetic (Down) | Synthetic (Down) |
Alt 5ʹ SS | |||||||
zipt-2.4 | 5ʹ SS | ATgtactgc | WT | WT | Up | Suppressed | Suppressed |