Table 2.
Crystallographic data collection and refinement statistics.
| adalimumab EFab | |
|---|---|
| Data Collection | |
| Space group | C2221 |
| Cell dimensions | |
| a, b, c (Å) | 125.4, 195.8, 48.8 |
| Resolution (Å) | 30.0–1.52 (1.54–1.52)a |
| Rsym | 11.5 (75.7) |
| I/σ(I) | 9.3 (2.0) |
| Completeness (%) | 99.6 (99.2) |
| Redundancy | 7.4 |
| Refinement b | |
| Resolution (Å) | 25 – 1.52 |
| No. of reflections | 92,219 |
| Rwork/Rfree | 0.153/0.179 |
| No. of residues | 436 |
| No. of waters/ions | 496/2 |
| RMSD bond lengths (Å) | 0.015 |
| RMSD bond angles (°) | 1.427 |
| B-factors (Å2) | 34.2 |
| Ramachandran regions (%) | |
| Favored/Allowed/Disallowed | 98/2/0 |
a Values in parenthesis are for highest resolution shell. b TLS groups were used in the refinement.