Table 2.

Association of H. pylori infection status with colonoscopy findings in patients with chronic atrophic gastritis who had MDM2 SNP309 G/G homozygosity and who underwent surveillance colonoscopy (univariate analysis)

Characteristics	H. pylori (−) (n=151)			H. pylori (+) (n=180)
	No. (%)	OR (95% CI)	p	No. (%)	OR (95% CI)	p
Colonoscopy findings
Overall CRN	13 (8.6%)	0.95 (0.75–1.21)	0.18	39 (21.6%)	3.89 (1.64–8.25)	0.02
Advanced CRN	8 (5.2%)	1.49 (0.57–1.48)	0.24	31 (17.2%)	4.24 (1.76–5.21)	0.01
Villous adenomatous polyp	1 (0.6%)	0.76 (0.52–1.47)	0.52	5 (2.7%)	1.03 (0.78–1.38)	0.36
Size of polyp≥1 cm	2 (1.3%)	1.14 (0.68–2.17)	0.61	9 (5.0%)	1.02 (0.86–2.13)	0.64
High-grade dysplasia or invasive adenocarcinoma	4 (2.6%)	1.24 (0.97–3.76)	0.14	14 (7.7%)	2.96 (1.48–4.71)	0.03
No. of adenoma≥3	1 (0.6%)	0.92 (0.71–1.48)	0.37	3 (1.6%)	1.05 (0.79–1.22)	0.47
Other CRN	5 (3.3%)	0.89 (0.56–1.24)	0.12	8 (4.4%)	1.14 (0.72–2.13)	0.09

OR: odds ratio; CI: confidence interval; CRN: colorectal neoplasm

Logistic regression was used to analyze the data

Adjustments were made by incorporating all relevant factors, such as age, gender, family history of colorectal cancer, body mass index, diabetes, hypertension, dyslipidemia, smoking, and alcohol consumption, into the analysis