Table 2.
Frequencies of the genotypes and alleles at TLR2 SNP rs4986790 in PU, AS, and NHS, total infected subjects (PU+AS), and total healthy subjects (AS+NHS)
| Genotype | PU | AS | NHS | Total infected subjects (PU+AS) | Total healthy subjects (AS+NHS) | p |
|---|---|---|---|---|---|---|
| TT | 34 (34.0%) | 50 (40.0%) | 56 (44.8%) | 84 (37.3%) | 106 (42.4%) | *0.25; **0.17; ***0.14 |
| CT | 50 (50.0%) | 55 (44.0%) | 39 (31.2%) | 105 (46.7%) | 94 (37.6%) | *0.05; **0.005; ***0.03 |
| CC | 16 (16.0%) | 20 (16.0%) | 30 (24.0%) | 36 (16.0%) | 50 (20.0%) | *0.54; **0.06; ***0.38 |
| T | 118 (59.0%) | 155 (62.0%) | 151 (60.4%) | 273 (60.7%) | 306 (61.2%) | *0.80; **0.94; ***0.59 |
| C | 82 (41.0%) | 95 (38.0%) | 99 (39.6%) | 177 (39.3%) | 194 (38.8%) | *0.80; **0.94: ***0.59 |
*
comparison of genetic variations between the PU and NHS groups
**
comparison of genetic variations between total infected subjects (PU+AS)
***
comparison of genetic variations between total healthy subjects (AS+NHS) and the PU group
AS: asymptomatic subjects; NHS: non-infected healthy subjects; PU: peptic ulcer; SNP: single nucleotide polymorphism; TLR: Toll-like receptors