Table 4.
The frequencies of the genotypes and alleles at TLR4 SNP rs3804099 in PU, AS, and NHS, total infected subjects (PU+AS), and total healthy subjects (AS+NHS)
| Genotype | PU | AS | NHS | Total infected subjects (PU+AS) | Total healthy subjects (AS+NHS) | p |
|---|---|---|---|---|---|---|
| AA | 77 (77.0%) | 103 (82.4%) | 95 (76.5%) | 180 (80.0%) | 198 (79.2%) | *0.42; **0.38; ***0.65 |
| AG | 18 (18.0%) | 15 (12.0%) | 25 (20.0%) | 33(14.7%) | 40 (16.0%) | *0.21; **0.20; ***0.64 |
| GG | 5 (5.0%) | 7 (5.6%) | 5 (4.0%) | 12 (5.3%) | 12 (4.8%) | *0.83; **0.57; ***0.93 |
| A | 172 (86.0%) | 221 (88.4%) | 215 (86.0%) | 393 (87.3%) | 436 (87.2%) | *0.66; **0.61; ***0.67 |
| G | 28 (14.0%) | 29 (11.6%) | 35 (14.0%) | 57 (12.7%) | 64 (12.8%) | *0.66; **0.61; ***0.67 |
*
comparison of genetic variations between the PU and NHS groups
**
comparison of genetic variations between total infected subjects (PU+AS) and the NHS group
***
comparison of genetic variations between total healthy subjects (AS+NHS) and the PU group
AS: asymptomatic subjects; NHS: non-infected healthy subjects; PU: peptic ulcer; SNP: single nucleotide polymorphism; TLR: Toll-like receptors